Low Dose Naltrexone Therapy (LDN)
Gentle Immune Modulation with Big Impact
At Hormonally Rooted, we embrace treatments that work with the body—quietly, powerfully, and holistically. Low Dose Naltrexone (LDN) is one such therapy that has been gaining momentum in the integrative and functional medicine space. Originally developed for other purposes, LDN has been shown to support the immune system, reduce chronic inflammation, and improve overall well-being in a wide range of conditions.
We offer LDN as a part of our personalized care plans, grounded in precision diagnostics, education, and ongoing support.
What Is Low Dose Naltrexone?
Naltrexone is a medication traditionally used at high doses for opioid addiction. In very small doses—usually between 0.5mg to 4.5mg daily—this same medication has a completely different mechanism of action. It works by temporarily blocking endorphin receptors, which prompts the body to produce more natural endorphins and upregulate immune system function.
This boost in endorphin levels can enhance pain modulation, mood, immune regulation, and cellular repair. The effects are gentle, gradual, and in harmony with the body’s natural rhythms.
Conditions LDN May Support
LDN is not a one-size-fits-all solution, but it has shown promise for many patients with chronic and inflammatory conditions, including:
- Autoimmune disorders (e.g., Hashimoto’s thyroiditis, multiple sclerosis, lupus, Crohn’s disease, rheumatoid arthritis)
- Chronic pain conditions (e.g., fibromyalgia, interstitial cystitis, endometriosis)
- Mood and neurological concerns (e.g., anxiety, depression, brain fog)
- Chronic fatigue and immune dysregulation
- Long COVID and post-viral syndromes
We use LDN as part of a broader, integrative plan—one that addresses root causes and not just symptoms.
How Does LDN Work?
LDN functions by temporarily blocking opioid receptors in the brain and immune system. This brief “blockade” triggers a rebound effect that increases the body’s production of endorphins and enkephalins—chemicals that play a key role in regulating the immune system and reducing inflammation.
Benefits May Include:
- Decreased chronic inflammation
- Reduced pain and muscle tension
- Improved immune resilience
- Enhanced sleep quality
- Elevated mood and mental clarity
- Better tolerance of other therapies
Because LDN works subtly over time, most patients begin to notice improvements after 3–6 weeks of consistent use.
Our Approach to LDN at Hormonally Rooted
We don’t believe in guessing—we believe in informed care. Every LDN consultation includes:
- A comprehensive health assessment
- Review of labs and existing diagnoses
- Guidance on dosing, timing, and titration
- Ongoing follow-up to monitor progress
- Coordination with your existing providers (if applicable)
We also partner with specialized compounding pharmacies to ensure the highest quality LDN prescriptions, tailored to your unique biochemistry.
Is LDN Right for You?
While LDN is well tolerated by most people, it’s not for everyone. It may not be appropriate for those taking opioid medications or those with certain liver conditions. We evaluate each patient carefully to determine whether LDN is the right step for their healing journey.
You are never just handed a prescription—you are guided, supported, and heard.
Learn More & Take the Next Step
To explore LDN further, we recommend visiting ldnresearchtrust.org, a respected source of education and research. Then, schedule a consultation at Hormonally Rooted to see whether LDN could be part of your integrative care plan.
Healing doesn’t always come with noise. Sometimes, it whispers. Low Dose Naltrexone is one of those quiet, powerful tools that can restore balance in the most gentle of ways.
Discover Personalized Wellness Solutions
Embark on a journey towards holistic health with our personalized consultations. At Hormonally Rooted LLC, we focus on creating a natural balance tailored to your unique needs. Connect with us today to explore how integrative wellness can support your path to mindful healing.